One of the things that when you begin your work... You've got your money. You've put your ads in the paper, or you've gone to the school. How do you keep it all together? It's really a complicated juggling act because you've got a lot of things happening.

The first thing you want to do absolutely is to get your data management act together and your project management. Get your data systems in place, particularly your implementation, because that's the only way you're going to be able to keep your eye on the ball and to understand how things are going, whether you're on track.

You want to keep to your timelines. I always say that, but I don't think I've ever, I don't know. I've probably been involved in 20 randomized trials, and by the end of the first year, I'm like 3 years behind, and then it's catch-up, catch-up. By the way, the more I do this, the more I'm, maybe I'm only a year behind after the first year. The whole idea is you need to get your info because you need to check and nurture the project daily.

It's sort of a big switch. Now, all of a sudden, you get the dough. All of a sudden, your focus completely changes, and it better change. You better not be sitting in your office drawing diagrams and models on the blackboard. You're now into making this happen, which means you're really trying to take care of your so-called support or infrastructure staff, and you have to be as obsessed by that as you are doing the stuff for a grant.