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Mark A. Frye

Mark A. Frye, M.D.

Dr. Frye’s research interests have centered on bipolar disorders, neurobiology of mood disorders and comorbid alcohol use. He is a 2006 recipient of a NARSAD Independent Investigator Award, for the use of MRS in examining neurobiology in unipolar and bipolar depression. For nine years, Dr. Frye was director of the Bipolar Disorder Research Program at UCLA, where he founded a chapter of the Depression and Bipolar Support Alliance.

Positions

  • Professor, Dept. of Psychiatry, Mayo Mood Clinic and Research Program, Mayo College of Medicine, Rochester, MN Director, Mayo Mood Disorders Research Program

 

Education

  • M.D., University of Minnesota, Minneapolis

 

Relevant Publications

  • Frye MA, Tsai GE, Huggins T. Low cerebrospinal fluid glutamate and glycine in refractory affective disorder. Biol Psychiatry. 2007;61:162—166.
  • Frye MA, Salloum IM. Bipolar disorder and comorbid alcoholism: Prevalence rate and treatment considerations. Bipolar Disord. 2006;8:677—685.
  • Frye MA, Calabrese JR, Reed ML. Healthcare resource utilization in bipolar depression compared with unipolar depression: Results of a United States population-based study. CNS Spectr. 2006;11:704—710.
  • Brook M, Hilty DM, Liu W, Hu R, Frye MA. Discharge against medical advice from inpatient psychiatric treatment: A literature review. Psychiatr Serv. 2006;57:1192—1198.
  • Leverich GS, Altshuler LL, Frye MA. Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizers. Am J Psychiatry. 2006;163:232—239.