Susanne Ahmari, MD, PhD
Dr. Ahmari is the Director of the Translational OCD Laboratory at University of Pittsburgh. Her lab uses cutting-edge technologies in rodents, including miniaturized head-mounted microscopes, optogenetics, and in vivo recording to identify brain changes linked to onset, persistence, and treatment of OCD-relevant behaviors. Findings from studies in patients are used to guide animal research in the lab. The overall goal is to discover brain abnormalities that lead to OCD and ultimately develop new treatments to help those affected. This work is supported by an NIMH BRAINS Award, Burroughs Wellcome Career Award, MQ Fellows Award, and NARSAD Young Investigator Award.
- Assistant Professor of Psychiatry, University of Pittsburgh, Pittsburgh, PA
- Director, Translational Obsessive Compulsive Disorder Laboratory, University of Pittsburgh, Pittsburgh, PA
- MD, Stanford University School of Medicine
- PhD, Stanford University School of Medicine
- Ahmari, S. E., Eich, T., Cebenoyan, D., Smith, E.E., and Simpson, H.B. (2014) Assessing neurocognitive function in psychiatric disorders: a roadmap for enhancing consensus. Neurobiology of Learning and Memory. Epub ahead of print. PMID: 24994503. NIHMSID: 617179.
- Cazorla, M., Osman, M. M., Delmondes de Carvalho, F., Shegda, M., Chuhma, N., Rayport, S., Ahmari, S. E., Moore, H., and Kellendonk, C. (2014). Striatal D2 receptors regulate the anatomical balance of basal ganglia circuitry. Neuron, 81, 153-164.
- Ahmari, S.E., Spellman, T., Douglass, N.L. , Khierbek, M.A. , Gordon, J., Deisseroth, K., and Hen, R. (2013) Repeated cortico-striatal stimulation generates chronic OCD-like behavior. Science, 7, 1234-1239. PMID: 23744948.
- Kheirbek M. A., Drew L. J., Burghardt N. S., Costantini D. O., Tannenholz L., Ahmari S. E., Zeng H., Fenton A. A., Hen R. (2013). Differential control of learning and anxiety along the dorsoventral axis of the dentate gyrus. Neuron, 77(5), 955-968. doi: 10.1016/j.neuron.2012.12.038
- Donaldson Z. R., Nautiyal K. M., Ahmari S. E., Hen R. (2013). Genetic approaches for understanding the role of serotonin receptors in mood and behavior. Curr Opin Neurobiol, 23(3), 399-406.
- Assess Mentorships Sooner Rather Than Later
- Basic Versus Clinical Focus
- Bridging Animal Model and Human Subject Research
- Building the Lab Around Interest
- Conducting Translational Neuroscience Research
- Find a Supportive Mentor When Pursuing Translational Research
- Look at Both Style and Science
- Publish All of It
- Qualities to Look For
- Starting the Lab
- Translational Versus Traditional Neuroscience