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 | Acceptance of Industry Restrictions Michelle Mello shares what she and her colleagues have learned while investigating researchers' acceptance of industry restrictions in clinical trials. Q&A |
| Achieving and Maintaining Data Integrity Linda Moody describes a method of maintaining data integrity during randomized clinical trials. Q&A |
 | Howard Abikoff explains how small data sets can still provide powerful evidence. Quick Tip - 2 minutes 51 seconds |
| Challenges in Studying Children with Bipolar Disorder There are methodology issues specific to studying children with severe mental illness, explains David A. Axelson. Quick Tip - 2 minutes 54 seconds |
 | Joseph R. Calabrese discusses COI issues in medical research. Presentation - 15 minutes 53 seconds |
| Consulting with a Statistician Sue M. Marcus talks about how a statistician can help with your research design. Q&A |
| Helena Kraemer defines the concept of Number Needed to Treat. Quick Tip - 1 minute 51 seconds |
| Roger S. McIntyre distinguishes remission from recovery. Quick Tip - 1 minute 49 seconds |
| Determining Clinical Significance Howard Abikoff describes a method for ascertaining whether a statistically significant difference is also clinically meaningful. Quick Tip - 3 minutes 21 seconds |
| Michael E. Thase offers tips on getting involved in multi-center trials. Quick Tip - 14 seconds |
| Helena Kraemer advances NNT as a way of communicating with clinicians. Quick Tip - 58 seconds |
| Deciding what inclusion/exclusion criteria to use is tricky, states Helena Kraemer. Quick Tip - 2 minutes 1 second |
| Lauren B. Marangell describes her litmus test for industry studies. Quick Tip - 58 seconds |
| Making Sense of Mediators and Moderators Helena Kraemer clarifies the roles of mediators, moderators, and interactions in RCTs. Q&A |
| Publishing negative trials isn't easy, but it's important for your field, believes Lauren B. Marangell. Quick Tip - 52 seconds |
| Quantifying Mood Disorders Is a Work in Progress Roger S. McIntyre underlines the importance of quantifying patient outcomes in the clinical realm. Quick Tip - 3 minutes 13 seconds |
| Husseini Manji advises investigators to address specific issues regarding comorbidity before beginning a study. Quick Tip - 1 minute 22 seconds |
| The Challenge of Heritability in Bipolar Research Family members with mental illness can effect data quality, states David A. Axelson. Quick Tip - 2 minutes 20 seconds |
| Helena Kraemer uses the perfect experiment to help her design a good study. Quick Tip - 1 minute 1 second |
| Thinking about the Benefit-Risk Ratio David J. Kupfer discusses Number Needed to Treat vs. Number Needed to Harm. Quick Tip - 4 minutes 1 second |
| To Include or Not Include Comorbidities Husseini Manji discusses why he generally chooses not to include comorbidities in research. Quick Tip - 1 minute 56 seconds |
| Understanding Clinical Equipoise Helena Kraemer explains clinical equipoise and its importance for randomized clinical trials. Q&A |
| Understanding and Managing Conflicts of Interest J. Bruce Smith defines conflicts of interest and shares how to handle them. Q&A |
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