Making Sense of Mediators and Moderators

Helena Kraemer clarifies the roles of mediators, moderators, and interactions in RCTs.

Q&A

Conflict of Interest

Joseph R. Calabrese discusses COI issues in medical research.

Presentation - 15 minutes 53 seconds

Achieving and Maintaining Data Integrity

Linda Moody describes a method of maintaining data integrity during randomized clinical trials.

Q&A

Questions About Comorbidity

Husseini K. Manji advises investigators to address specific issues regarding comorbidity before beginning a study.

Quick Tip - 1 minute 22 seconds

The Gedank Experiment

Helena Kraemer uses the perfect experiment to help her design a good study.

Quick Tip - 1 minute 1 second

Publishing Negative Findings

Publishing negative trials isn't easy, but it's important for your field, believes Lauren B. Marangell.

Quick Tip - 52 seconds

To Include or Not Include Comorbidities

Husseini K. Manji discusses why he generally chooses not to include comorbidities in research.

Quick Tip - 1 minute 56 seconds

Understanding Clinical Equipoise

Helena Kraemer explains clinical equipoise and its importance for randomized clinical trials.

Q&A

Including Comorbidities

Deciding what inclusion/exclusion criteria to use is tricky, states Helena Kraemer.

Quick Tip - 2 minutes 1 second

Quantifying Mood Disorders Is a Work in Progress

Roger S. McIntyre underlines the importance of quantifying patient outcomes in the clinical realm.

Quick Tip - 3 minutes 13 seconds